Family Name: PAPILIONACEAE
Botanical Name : GLYCYRRHIZA GLABRA
Common Name: CALAMUS, MULETHI, SWEET LIQUORICE, SWEETWOOD
Part Used: ROOT
Licorice Root is also known by the names Liquorice, Yashtimadhu, The Great Harmonizer, Grandfather Herb, and Sweetwood.
Liquorice Uses : Licorice is a traditional herbal remedy with an ancient history and world wide usage. Modern research has shown it to have effects upon, amongst other organs, the endocrine system and liver. It is Tonic, Diuretic, Demulcent, Expectorant, Emenagogue Laxative and Laxative. Used for allaying coughs and catarrhal infections. As an anti-hepatotoxic licorice is effective in the treatment of chronic hepatitis and cirrhosis, for which it is been widely used in Japan
Licorice Root is most commonly used for treating upper respiratory ailments including coughs, hoarseness, sore throat, and bronchitis. The main constituent found in the root is glycyrrhizin. This unique active substance has been shown to possess anti-viral and anti-inflammatory properties; it has also been shown to be effective in the fight against the HIV virus. Liquorice is used in allopathic medicine as a treatment for peptic ulceration, a similar use to its herbal use in gastritis and ulcers. It can be used in the relief of abdominal colic.
Rarely used alone, it is a common component of many herbal teas as mild laxative, a diuretic, and for flatulence. It has also been known to relieve rheumatism and arthritis, regulate low blood sugar, and is effective for Addison's disease. The root extract produces mild estrogenic effects, and it has proven useful in treating symptoms of menopause, regulating menstruation, and relieving menstrual cramps.
The herb is extensively cultivated in Russia, Spain, Iran and India. Liquorice is one the most popular and widely consumed herbs in the world.
Many people enjoy liquorice's sweet taste and beneficial effects, which include counteracting toxic effects, toning the spleen and increasing energy. "It is especially beneficial to smokers because of the anti-inflammatory action. Rhizomes in Licorice have a high mucilage content which, when mixed with water or used in cough drops, sooths irritated mucous membranes. The use of Licorice also has an expectorant effect which increases the secretion of the bronchial glands.
"It is also famous for its fast, soothing relief from indigestion and cases of peptic ulcers. It lubricates the stomach and lungs and reduces muscle tension and irritability.
Liquorice is the second most prescribed herb in China followed by ginseng. he constituent glycyrrhizin is 50 times sweeter than sugar, making Licorice a widely used ingredient in the food industry. The distinctive flavor of Licorice Root makes it a popular additive to baked confections, liqueurs, ice cream and candies
Licorice has also been used in poultices for control of dermatitis and skin infections. It helps to open the pores and is used in combination with other cleansing and healing herbs as an emollient.
Beneficial for hypoglycemia , bronchitis , consumption , colitis , cystitis , general debility, stomach ulcers , diverticulosis, indigestion , gastritis, bladder irst, fevers, nausea, and inflammation . Cleanses the colon, lowers blood cholesterol , p, kidney ailments , stress, colds, coughs, laryngitis or hoarseness, sore throats , relieves thromotes adrenal gland function, decreases muscle or skeletal spasms, and increases fluidity of mucus from the lungs, coughs, hoarseness, mucous congestion, and bronchial tubes . Has estrogen-like hormone effects; changes the voice.
Memory-strengthening activity of Glycyrrhiza glabra in exteroceptive and interoceptive behavioral models.
Parle M, Dhingra D, Kulkarni SK.
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University, Hisar, Haryana, India. firstname.lastname@example.org
In the traditional system of medicine, the roots and rhizomes of Glycyrrhiza glabra have been employed clinically for centuries for their anti-inflammatory, anti-ulcer, expectorant, antimicrobial, and anxiolytic activities. The present study was undertaken to investigate the effects of G. glabra, popularly known as liquorice (Mulathi), on learning and memory. The elevated plus-maze and passive avoidance paradigm were employed to evaluate learning and memory parameters. Three doses (75, 150, and 300 mg/kg p.o.) of aqueous extract of G. glabra were administered for 7 successive days in separate groups of mice. The dose of 150 mg/kg of the aqueous extract of liquorice significantly improved learning and memory of mice. Furthermore, this dose reversed the amnesia induced by diazepam (1 mg/kg i.p.), scopolamine (0.4 mg/kg i.p.), and ethanol (1 g/kg i.p.). Anti-inflammatory and antioxidant properties of liquorice may be contributing favorably to the memory enhancement effect. Since scopolamine-induced amnesia was reversed by liquorice, it is possible that the beneficial effect on learning and memory may be because of facilitation of cholinergic transmission in brain. However, further studies are necessitated to identify the exact mechanism of action. In the present investigation, G. glabra has shown promise as a memory enhancer in both exteroceptive and interoceptive behavioral models of memory.
Inhibitory effect of 18beta-glycyrrhetinic acid on 12-O-tetradecanoyl phorbol-13-acetate-induced cutaneous oxidative stress and tumor promotion in mice.
Agarwal MK, Iqbal M, Athar M.
Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), New Delhi, India.
Glycyrrhetinic acid is an aglycone of glycyrrhizic acid, another major active component of licorice roots. Licorice root extract has been used for a long time as a medicine and a natural sweetening additive. In the present study, we found that glycyrrhetinic acid inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA) mediated oxidative stress and tumor promotion in murine skin. Topical application of TPA alone in mouse skin enhances ornithine decarboxylase activity and also increases [(3)H]-thymidine incorporation in DNA. Topical application of TPA also resulted in the depletion of glutathione, activities of glutathione metabolizing and antioxidant enzymes. Application of glycyrrhetinic acid prior to TPA treatment reduces this enhanced ODC activity, [(3)H]-thymidine incorporation in DNA and oxidative stress. Glycyrrhetinic acid was also found to inhibit DMBA/TPA-induced skin tumor formation at doses of 1.25 and 2.5 mg by reducing the number of tumors per mouse by 24% (P < 0.05) and 62% (P < 0.05), respectively. These results suggest that glycyrrhetinic acid, an antioxidant, is a potential chemopreventive agent that can inhibit DMBA/TPA-induced cutaneous oxidative stress and tumor promotion.